Engineer better
proteins, faster.

Engineer better
proteins, faster.

Engineer better
proteins, faster.

Leverage AI to generate protein candidates and improve their properties. More breakthroughs in fewer experiments — guided by your own experimental data.

Leverage AI to generate protein candidates and improve their properties. More breakthroughs in fewer experiments — guided by your own experimental data.

Leverage AI to generate protein candidates and improve their properties. More breakthroughs in fewer experiments — guided by your own experimental data.

data ui
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Generate candidates

Track round status easily, from generating candidates to uploading experimental results.

Explore reports

Manage data

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Generation

Reports

Data

OUR CUSTOMERS

OUR CUSTOMERS

Trusted by the world's top Biopharma and Industrial Bio R&D teams

Through our partnership with Cradle, we are embedding advanced Al directly into how we innovate, enabling our teams to shorten development time and bring real-world biosolutions faster to market.

Claus Fuglsang Crone

Chief Scientific Officer, Novonesis

PROTEIN ENGINEERING 2.0

PROTEIN ENGINEERING 2.0

Better results across
all your properties

Better results across
all your properties

Compounding results
across all properties.

Get products to market in quarters, not years. Use Cradle to chart the fastest course to proteins that meet all your desired objectives. Explore further, optimize faster, and reach your destination in fewer experiments.

Get products to market in quarters, not years. Use Cradle to chart the fastest course to proteins that meet all your desired objectives. Explore further, optimize faster, and reach your destination in fewer experiments.

+300%

+300%

T7 RNA

T7 RNA

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Round Progress

Round Progress

with Cradle

with Cradle

Compounding results

Move from incremental progress to compounding results with models that learn from every round of your wet lab data. Teams that use Cradle report 2-12x faster development timelines.

Breakthroughs on repeat

Following a single path puts you at risk of hitting a dead end. Instead, confidently explore multiple design strategies to bring more programs over the finish line and strengthen your IP portfolio.

All projects

All projects

mAb-HER2

mAb-HER2

Round 4

Round 4

mAb-TNF

mAb-TNF

Completed

Completed

vax-HPV9

vax-HPV9

Completed

Completed

Binding affinity

Specificity

Activity

Stability

Expression

Radar chart comparing antibody characteristics: binding affinity, specificity, activity, expression, and stability.  Light blue and yellow-green lines show different antibody performance.
Radar chart comparing antibody characteristics: binding affinity, specificity, activity, expression, and stability.  Light blue and yellow-green lines show different antibody performance.

Co-optimize all your properties

Activity, binding, stability, expression, and more. Co-optimize the properties you care about, turning complex trade-offs into optimized solutions in fewer rounds.

WORK ON ANY PROTEIN

WORK ON ANY PROTEIN

Bring any protein
and all properties

Accelerate your journey from hit identification to lead optimization and beyond. If you can measure it, you can optimize it with Cradle. 

This makes Cradle fit-for-purpose for teams developing therapeutics, agricultural solutions, food ingredients, and more.

Antibodies

Craft mature and developable binders that avoid unwanted immunogenicity.

Antibodies

Craft mature and developable binders that avoid unwanted immunogenicity.

Antibodies

Craft mature and developable binders that avoid unwanted immunogenicity.

Enzymes

Accelerate specific catalytic conversions, even in challenging conditions.

Enzymes

Accelerate specific catalytic conversions, even in challenging conditions.

Enzymes

Accelerate specific catalytic conversions, even in challenging conditions.

Vaccines

Stabilize your antigens and hit therapeutic goals faster.

Vaccines

Stabilize your antigens and hit therapeutic goals faster.

Vaccines

Stabilize your antigens and hit therapeutic goals faster.

Peptides

Get to desired efficacy while ensuring stability.

Peptides

Get to desired efficacy while ensuring stability.

Peptides

Get to desired efficacy while ensuring stability.

BUILT FOR ENTERPRISE

BUILT FOR ENTERPRISE

Private. Secure. Yours.

With Cradle, your sequences and data remain private, secure, and entirely yours. Only you and those you invite can access your data, which is never used to train models for others. Protected by bank-grade security, your data stays secure at all times.

Plus, you retain full ownership of your intellectual property—no royalties, just a software subscription fee.

Privacy-first AI

Privacy-first AI

You experimental data is only used to train your organizations custom models.

SOC 2 compliant

SOC 2 compliant

Cradle is fully SOC 2 compliant with active monitoring and tight security protocols in place.

Single Sign-on

Single Sign-on

Secure and simple account management with SSO support for Google and Microsoft.

Custom predictors

Custom predictors

BETA

BETA

Use internally developed predictors right in Cradle and see outputs inside Reports.

Zero-maintenance

Zero-maintenance

Fully managed AI infrastructure with optimized GPU that scales with your need.

Dedicated support

Dedicated support

Our team of scientists and ML experts are ready to assist with any issues.

THE CRADLE LAB

THE CRADLE LAB

AI that gets better
every two weeks

Cradle isn’t a CRO, so why do we run our own wet lab in Amsterdam?

It's simple. So you get reliable and high-performing models from day one, while your proprietary data remains completely private. 

Much like a self-driving car company: they wouldn’t just design algorithms and cross their fingers. They need to test real-world scenarios and collect data in order to fine-tune performance. We take the same approach, ensuring our models are performant even before seeing your data.

You made it. Nice.
Now, let's talk?

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© 2026 · Cradle is a registered trademark

Built with ❤️ in Amsterdam & Zurich

© 2026 · Cradle is a registered trademark

Built with ❤️ in Amsterdam & Zurich